Flying by the Seat of Our Pants

With the Food and Drug Administration's (FDA) recent approval of two protease inhibitors, there are now eight anti-HIV drugs on the market, compared to only four last year. Viral load testing may help doctors make sense of therapeutic options, which frequently involve combination therapy. A survey of several leading AIDS treatment clinicians from North America, Europe and Australia shows a wide diversity in care provided. Many doctors remain concerned about toxicity and cross-resistance, and all are aware of the economic implications of aggressive drug treatment for AIDS.